Breast cancer occurs when cells in the breast start out from control to grow and nearby tissue and then penetrate During the body able to spread. Large collections of this tax from tissue tumors called out to be. However, some tumors are not really cancer because they do not distribute or someone life threatening able. These are called benign tumors. The tumors that would ¤ during the body distribute or invade nearby tissue able to apply as cancer and will be sartige called tumors. Theoretically able to have any type of tissue in the breast cancer one, but he usually comes either from the Luftschachten or by the Dra ¼ sen. Because he months to years, so a tumor large enough erhà ¤ lt in the chest to believe we scan for tumors with r mammogram, the disease sometimes able to see before we believe it can be activated.
How can I prevent breast cancer?
The main risk factors for the development of breast cancer awareness can not by the individual can be controlled. There are some risk factors, to a danger relate, but there is not a clear cause and effect Verhaeren ¤ ltnis. Can be no strong recommendations as the cause and effect Verhaeren ¤ ltnis formed with tobacco and lung cancer will be seen. There are some risk factors identified by a woman as amended will be able to promote the development of breast cancer might affect.
If possible, should a woman long-term hormone replacement therapy to avoid breast cancer treatment, has children before age 30, breastfeeding, avoiding weight gain by bung and correct and limited alcohol consumption at 1 Getrà ¤ nk one day or less. Invitation to women already on a riskier, their risk of developing breast cancer by approximately 50% be reduced by a drug from taking the tamoxifen for r five years is called. Tamoxifen has some side effects often , which is not serious and some rare side effects which are fatal. Tamoxifen is not available to prevent the most used, but may be useful in some cases. There are limited data that suggest that vitamin A against breast cancer , but further research is needed before it is available to prevention can be recommended.
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The type histology (tissue) of breast cancer is an important factor in determining the prognosis of the disease. From the cancerous tissue is removed by surgical biopsy or open drain-needle biopsy with a large calibre.
The breast cancers may be classified in one of 2 following categories:
NON INVASIVE CARCINOMA IN SITU:
Ductal carcinoma in situ:
Frequency-> 2-3% of breast cancers. No palpable. The ductal carcinoma in situ or non-invasive (DCIS ductal carcinoma in situ) is a form of pre-invasive breast cancer. It is a cancer that is confined to the epithelial cells of light channels.
Lobular carcinoma in situ:
Frequency-> 2-3% of breast cancers. No palpable. The lobular carcinoma in situ (LCIS lobular cancer in situ) is also a form of pre-invasibve of breast cancer treatment.
INVASIVE CARCINOMA:
Infiltrating Ductal carcinoma: This is the most common cancer-> 70-80% of breast cancers. It includes a variety of types including histological group without specific histological type known in English NOS (Not Otherwise Specified), which is the most common.
Medullary Carcinoma invasive: Frequency-> 5-8% of breast cancers. Grosse solid well-defined lesion often encountered among younger women and pre-ménopausées.Fréquence 5% -7% of breast cancers.
Carcinoma tubular: Frequency-> 1-2% of breast cancers. Often multicenter, bilateral with a family history of breast cancer. The axillary lymph node metastases are rare and the prognosis is better than infiltrating ductal carcinoma NOS.
Other less common carcinoma: Frequency-> less than 1% of breast cancers. Compared with invasive ductal carcinoma, they often have a relatively good prognosis.
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The goal of therapy for early-stage breast cancer is cure, and there are many ways to get there. Different treatment choices will often be associated with different side effect profiles, and that’s where we have to have a long discussion weighing the risks and benefits of different approaches.
For early-stage breast cancer info, most people will say they’re willing to put up with fairly substantial side effects in the short run because their hope is that they will never hear from the cancer again. If we’re going to think of a scale, it will be tipped towards more toxicity for more benefit. When we’re treating advanced breast cancer treatment,however the scale may be tipped the other way. People may not want to deal with a whole lot of toxicity or give up quality of life for very marginal benefits. So these are the kinds of decisions that come into play.
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A team of researchers at the University of Michigan has succeeded in creating the equivalent of nanotechnological Trojan horse to carry a very powerful chemotherapy treatment within a tumor cells, thereby increasing the drug’s ability to kill breast cancer and reducing side effects toxic.
According to a press release circulated yesterday by the University, previous studies in cell cultures have shown that the use of nanoparticles to transport anti-cancer treatments directly to the objective, namely the tumor cells, could increase the therapeutic response. Now scientists from Michigan have shown that this treatment based on nanotechnology, is effective in live animals.
According to the study director, Professor James Baker, “This is the first study that has shown as a medicine transported by a nanoparticle can leave the bloodstream, reaching the breast cancer cells and have a biological impact on the tumor of the animal. ”
Baker stresses the optimism of his team before this achievement because in his opinion shows that nanotechnology can dramatically improve current therapies against cancer. “Send treatments directly to breast cancer cells reduces the amount reaching normal cells, increases the impact of anti-carcinogenic medicine and reduces their toxicity. By improving the therapeutic index of cancer drugs, our goal is to convert cancer into a chronic but manageable.
The survey results are published in the number of June 15, 2005 in the journal Cancer Research.
The vehicle for carrying the drug used by scientists from Michigan is a polymer molecule called a dendrimer whose diameter measured less than five nanometers. These Dendrimers are small enough to pass through a tiny openings in cell membranes.
— This image of a dendrimer provided by the University of Michigan shows its structure as a tree with many branches on which scientists can join a variety of molecules, including drugs.
In experiments developed by the team of Prof.. Baker, researchers adhered methotrexate, a potent anti-cancer drug, to branches of the dendrimer. In other areas, adhered fluorescent imaging agents and a secret ingredient, folic acid.
Folic acid is an important vitamin required for the healthy functioning of all cells. But it appears that cancer cells need more folic acid than normal. By leveraging its appetite for this substance, scientists succeed in preventing cancer cells develop resistance to drugs chyme therapeutic.
In the tests conducted in the laboratory, this new therapy nanoparticles in mice that received injections of human cancer cells was 10 times more effective and less toxic than the traditional administration of treatment.
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Like every year with the arrival of good weather also increases the concern of dermatologists for the damage they commit to our skin with abusive exposures to the sun so characteristic of today’s society. Indeed, there is still a major disregard for the serious implications that this practice causes.
Thus, according to data from a study by the association of European League Against breast Cancer and Garnier Delial, people who show a risk behaviour in the sun correspond to the profile of “men and boys” in a 66 per percent. In addition, nearly 50 percent of consumers still “does not assume the risk or adopts behaviors against the sun,” according to Juan Alonso de Lomas, CEO of this company in Spain.
The study concludes that France is the country that uses less protection for children, while England is the largest protected. Meanwhile, Spaniards are among the citizens more aware of the harmful effects that may have a bad sun exposure and Italy is the country that gives more importance to tan from the aesthetic point of view.
Principal result: melanoma
The excess sun exposure is responsible for skin breast cancer worse prognosis: melanoma, tumors whose incidence has increased in Spain in recent years and continues to do so, although not as mortality, thanks to increased early diagnosis of disease As highlights the Spanish Academy of Dermatology and Venerology (AEDV).
Specifically, melanoma ranks 17 th place frequently in respect of all aluminium and parabens in men in Europe and 8 th in women. Spain, along with Portugal and other countries of the Mediterranean, is one of the countries of Europe with lower incidence of melanoma, with an adjusted rate per 100,000 inhabitants in 1998 of 5.85 to 7.50 for men and women, compared for example to Sweden, where he was from 16.08 and 15.00 respectively.
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